Article Text
Abstract
A 3 year, 9 month old child with pica presented with a blood lead concentration of 1.74 μmol/l (360 μg/l). The source of poisoning was snooker chalk (lead content 7200 μg/g). She was treated with intravenous calcium disodium edetate chelation. Thirty months later her blood lead was 0.39 μmol/l (80 μg/l). This case illustrates the need to be vigilant for more unusual causes of lead poisoning in the home.
- lead poisoning
- chelation treatment
Statistics from Altmetric.com
Mean blood lead concentrations in the United Kingdom have fallen over the last 10 years, by a factor of 3.6 to 5.0 in children.1 This is due to the reduced use of leaded paint and lead solder in food tins, improved industrial hygiene, and increased unleaded petrol use. However, cases of clinically significant lead poisoning continue to occur.2 This case report illustrates the difficulties that can arise in trying to identify the source of lead poisoning in a child.
Case report
A 3 year, 9 month old girl was taken to her general practitioner with a suspected viral upper respiratory tract infection. Further questioning revealed that she had a poor diet; she would only drink milk and was not interested in solid foods. She had a 9 to 12 month history of pica of soil and concrete. There was no history of constipation or bony/abdominal pain. Her previous medical history included mild eczema and wheezing with upper respiratory tract infections. She was the product of a normal delivery and had normal developmental milestones. She was not on regular medication. Her parents were from India, but she had been born and brought up in the UK.
On examination, her weight and height were on the 3rd centile, and she had conjunctival pallor. Neurological examination was unremarkable.
Initial blood results revealed a haemoglobin level of 6.3 g/dl, mean corpuscular volume 57.2 fl, mean corpuscular haemoglobin 17.4 pg, and blood lead concentration 1.74 μmol/l (360 μg/l, table 1). She was started on iron supplements in view of the microcytic, hypochromic anaemia (ferrous fumarate 5 ml twice daily, equivalent to 90 mg elemental iron daily).
Blood lead (μmol/l) and haemoglobin (g/dl)
An environmental assessment was carried around the home out to identify the source of lead poisoning. Samples taken included paint, plaster, and dust (lead concentrations 98 μg/g, 0 μg/g, and 0 to 49 μg/g respectively); soil samples (lead concentration 12 μg/g); and a first run morning water sample (lead concentration 16 μg/l). The parents were questioned to try to identify any other lead source, particularly via the use of alternative medicines or surma cosmetics, but there was no such history.
Over the next 18 months, her dietary intake remained poor and she was reluctant to take the iron supplements. Her blood lead initially fell (table 1) to 1.16 μmol/l (240 μg/l) in March 1997. However, it rose again to 2.22 μmol/l (460 μg/l) in July 1997, and she remained anaemic (haemoglobin 10.4 g/dl). A course of chelation treatment was prescribed, in line with our unit's lead poisoning protocol and American Academy of Pediatrics guidelines.3Because of her previous poor compliance with oral medication, she was not given oral DMSA (meso-2, 3-dimercaptopropanesulphonate), but was admitted for a 5 day course of intravenous calcium disodium edetate 1000 mg/m2 daily, in two divided doses. She tolerated this well and her blood lead fell to 0.68 μmol/l (140 μg/l) 14 days after chelation. Further detailed questioning of her parents whilst she was an inpatient revealed that she was often seen with snooker chalk in her mouth. This chalk (fig 1) was obtained for analysis and showed a lead content of 7200 μg/g.
Picture of the snooker chalk
Three months after chelation treatment, her haemoglobin level had risen to 12.2 g/dl and her blood lead was 1.16 μmol/l (240 μg/l), in keeping with redistribution of lead to blood from bone stores. She was lost to follow up until January 1999, when her haemoglobin was 12.5 g/dl and blood lead 0.63 μmol/l (130 μg/l). Her height was on the 40th centile and weight on the 25th centile, and she was progressing normally in school.
Blood lead analysis was carried out using graphite furnace spectrophotometry, and environmental samples were analysed using flame spectrophotometry (IMH).
Discussion
Exposure to lead in children may occur from environmental sources in the home, recreational sources, or occupational sources via parents. Common sources include leaded paint, lead contaminated dust and soil, airborne lead from leaded petrol and industrial emissions, water contaminated by lead pipes, and food contaminated by lead soldered cans or leaded ceramics.4 Lead poisoning has also been reported from the use of surma cosmetics,5 following ingestion of a lead foreign body,6 due to lead gunshot pellets,7 and following the use of traditional remedies such as ayurvedic medicines.8
A thorough environmental history, including questioning to exclude unusual sources, is crucial in assessing children with lead poisoning. Ideally, samples should be obtained from the home for analysis to help identify sources and prevent further exposure. This case illustrates that unusual lead sources should always be considered, particularly when common sources have been excluded. Identification of the source of lead poisoning is important because removal of the source is much more effective than chelation treatment in the long term.
This is the first case of lead poisoning due to snooker chalk in Europe. There has been one previous report, from the United States, of snooker chalk as a source of lead: two children were found to have raised blood lead concentrations of 1.69 μmol/l (350 μg/l) and 1.26 μmol/l (260 μg/l) during a routine screening programme (with snooker chalk lead contents of 4030 and 7000 μg/g respectively).9
When snooker chalk is used, a fine dust is formed that will contaminate the snooker table, floor, clothes of the user, and surrounding soft furnishings. Pica of contaminated snooker chalk will provide a considerable risk, as the World Health Organization tolerable daily intake of lead is 3.5 μg/kg.10 A 15 kg, 4 year old child would only need to ingest 7.4 mg of snooker chalk (with a lead content of 7000 μg/g) per day to be at risk of lead accumulation. Snooker chalks therefore pose a significant risk to young children and “lead free” snooker chalks should be used preferentially, particularly if children are in the home.
Linked Articles
- Rapid responses