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Indirect measurements of sweat electrolyte concentration in the laboratory diagnosis of cystic fibrosis
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  • Published on:
    Sweat chloride and conductivity

    Dear Editor

    As I understand the Scientific Method, a statement purporting to be factual, either in a scientific article or in a discussion with peers, must be supported by cited evidence that may be publicly examined for its scientific veracity.

    The paper by Heeley et al provides data to illustrate the equivalence of conductivity and chloride in cystic fibrosis (CF) diagnosis,[1] and therefore corrob...

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    Conflict of Interest:
    None declared.
  • Published on:
    Re: Sweat chloride and conductivity
    Dear Editor

    As the principal author of the NCCLS guideline on sweat testing methodology, Dr Le Grys should be better informed of its content. It includes the clear statement that when sweat test results are obtained by conductivity measurement "the patient should be referred for quantitative sweat electrolyte testing". In our paper we refer to this statement as implying that sweat conductivity measurement should be re...

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    Conflict of Interest:
    None declared.
  • Published on:
    Sweat chloride and conductivity
    Dear Editor

    As a principal author of the sweat testing document published by National Committee for Clinical Laboratory Standards (NCCLS) and consultant to the Cystic Fibrosis Foundation (CFF)(US), I write to address an inaccuracy in the article by Heeley et al (Indirect measurement of sweat electrolyte concentration in the laboratory diagnosis of cystic fibrosis. Arch Dis Child 2000;82:420-4). The authors misrepresent...

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    Conflict of Interest:
    None declared.