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Vagal nerve stimulation for epilepsy
  1. RICHARD O ROBINSON, Professor of Paediatric Neurology
  1. Guy's & St Thomas's Hospital Trust
  2. Newcomen Centre, Guy's Hospital
  3. St Thomas Street, London SE1 9RT, UK

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    Editor,—It is timely that “Archivist” has taken an interest in vagal nerve stimulation for epilepsy. The comments do not suggest however that Archivist was fully informed.

    It is true to say that the mechanism by which the effect is achieved is not known, but there is considerable animal evidence that both serotoninergic and noradrenergic pathways from afferent vagus terminations to the thalamus are involved.1 …

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