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Letters to the editor
IGFBP-3 as a predictor of growth hormone deficiency
  1. B BIELINSKI,
  2. N J SHAW,
  3. P M CLARK
  1. Department of Endocrinology
  2. Birmingham Children's Hospital, Birmingham B4 6NH, UK

    https://doi.org/10.1136/adc.82.3.266k

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      Editor,—We read with interest the paper by Mitchell and colleagues1 and wish to add our own observations on this subject. In 1996 the Regional Endocrine Laboratory started to provide a service for the measurement of insulin-like growth factor binding protein (IGFBP-3) following early reports that this was a good marker of growth hormone secretion. We then undertook a retrospective audit of the measurement of serum insulin-like growth factor (IGF-1) and IGFBP-3 as predictive markers of growth hormone deficiency (GHD) in children undergoing growth hormone …

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