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Reduced bone mineral density at completion of chemotherapy for a malignancy
  1. BERNADETTE BRENNAN, Consultant Paediatric Oncologist
  1. Royal Manchester Children’s Hospital
  2. Pendlebury, Manchester M27 4HA, UK
  3. Christie Hospital NHS Trust
  4. Withington, Manchester M20 9BX, UK
    1. S M SHALET, Professor in Endocrinology
    1. Royal Manchester Children’s Hospital
    2. Pendlebury, Manchester M27 4HA, UK
    3. Christie Hospital NHS Trust
    4. Withington, Manchester M20 9BX, UK

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      Editor,—The paper by Arikoski and colleagues1 provides useful information on bone mineral density (BMD) in survivors of childhood acute lymphoblastic leukaemia (ALL), and the results are consistent with other reports.2 3 However, we are disappointed in the heterogeneity of the cohort of other malignancies and the major differences in each patient’s treatment, as potentially the disease type and the nature of the cancer therapy may have an effect on BMD.

      A significant proportion of the other malignancy cohort had radiation directly to or near …

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