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Umbilical cord blood transplantation
  1. C A JONES,
  1. Child Health, School of Medicine
  2. University of Southampton
  3. Southampton, SO16 6YD, UK

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    Editor,—Although Will1 gave an informative overview of umbilical cord blood transplantation he expressed the commonly held misconception that umbilical cord blood lymphocytes are immunologically naïve. To call these cells immunologically naïve implies that the B and T lymphocytes have not encountered antigen. This is clearly not the case. Numerous groups have demonstrated antigen specific responsiveness at birth …

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