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Treatment of nephrogenic diabetes insipidus with hydrochlorothiazide and amiloride
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  • Published on: 22 March 2016
    An alternative to hydrochlorothiazide

    Nephrogenic diabetes insipidus (NDI) is characterised by the inability of the kidney to concentrate urine in response to arginine vasopressin. The consequences are severe polyuria and polydipsia, often associated with hypertonic dehydration. Intracerebral calcification, seizures, psychosomatic retardation, hydronephrosis, and hydroureters are its sequelae. In this study, four children with NDI were treated with 3 mg/kg/...

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    Conflict of Interest:
    None declared.