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The Nikolsky sign in staphylococcal scalded skin syndrome
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Editor,—Ladhani and Evans, in their account of staphylococcal scalded skin syndrome (SSSS),1accurately describe “large fluid-filled bullae which quickly rupture on slightest pressure” but incorrectly call this the Nikolsky sign. Fragility of blisters merely reflects their superficial position in the epidermis. The Nikolsky sign is dislodgement of intact superficial epidermis by a shearing force, indicating a plane of cleavage in the …