You are here

Article Text

Article menu
Download PDFPDF
Original article
Hepatitis GB virus-C/hepatitis G virus infection in liver disease
  1. Ikuo Nagataa,
  2. Nikos Tzampourasb,
  3. Shilpa Chokshib,
  4. Nikolai V Naoumovb,
  5. Paul Cheesemanc,
  6. Heather M Smithd,
  7. Alastair J Bakerc,
  8. Roger Williamsb,
  9. Giorgina Mieli-Verganie
  1. aDepartment of Child Health, King’s College School of Medicine and Dentistry and Institute of Hepatology University College London Medical School, London, bInstitute of Hepatology University College London Medical School, London, cKing’s College Hospital, London: Department of Child Health, dInstitute of Liver Studies, eDepartment of Child Health, King’s College School of Medicine and Dentistry, London
  1. and reprint requests to: Dr Alastair J Baker, Department of Child Health, King’s College Hospital, Denmark Hill, London SE5 9RS.

Abstract

Hepatitis GB virus-C (HGBV-C)/hepatitis G virus (HGV) infection was investigated in 106 children with liver disease (54 boys and 52 girls, mean age 7.3 years); 12 with chronic hepatitis C virus infection, 29 with positive hepatitis B surface antigen, nine with idiopathic fulminant hepatic failure, seven with graft dysfunction after liver transplantation associated with autoimmune features, 20 with cryptogenic liver disease, and 29 with autoimmune liver disease. HGV RNA detected by reverse transcription polymerase chain reaction was found to be positive in 4/106 patients (3.8%). Risk factors were identified in three patients, including blood transfusion and/or medical treatment in Eastern Europe. The prevalence was higher than that of blood donors but lower than that of 2 adult patients with liver disease. HGV is not associated with any specific disease group and does not seem to be a major aetiological agent of liver disease in childhood in the UK.

  • hepatitis G virus
  • routes of infection
  • epidemiology

https://doi.org/10.1136/adc.77.3.223

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes