Article Text

Download PDFPDF
Chronic bullous disease of childhood and a paecilomyces lung infection in chronic granulomatous disease
  1. J H Sillevis Smitta,
  2. J H W Leusenb,c,
  3. H G Stasb,
  4. A H Teeuwb,
  5. R S Weeningb,c
  1. aUniversity of Amsterdam, Netherlands: Department of Dermatology, bEmma Children’s Hospital, cCentral Laboratory of the Netherlands Red Cross Blood Transfusion Centre
  1. Dr Sillevis Smitt, Department of Dermatology, AO-228, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands.

Abstract

A 12 year old boy suffering from p67-phoxdeficient chronic granulomatous disease presented with a bullous skin disease and a lung infection with paecilomyces species. The histopathology of a bullous lesion showed subepidermal blister formation and microabcesses containing eosinophils in the dermal papillae. By direct immunofluorescence, linear staining of IgA at the dermal-epidermal junction was detected which confirmed the clinical diagnosis of chronic bullous disease of childhood (linear IgA dermatosis)

  • chronic granulomatous disease
  • chronic bullous disease
  • paecilomyces
  • p67-phox

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes