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White matter attenuation and megalencephaly
  2. T COX
  1. Newcomen Centre
  2. Guy’s Hospital, St Thomas’ Street
  3. London SE1 9RT

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    Editor,—In 1985 one of us (ROR) published a case of unusual self resolving leukodystrophy.1 We now describe a second case. As with the first, neuroimaging was prompted by a large head size. At 14 months, she had an occipitofrontal circumference of 53.5 cm some 4 SDs above the mean. Her father’s head circumference was similarly increased being 63 cm. His …

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