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Abnormal technetium labelled white cell scan in the colitis of chronic granulomatous disease
  1. S Hoarea,
  2. J E Walsha,
  3. E Easthamb,
  4. M A Abinuma,
  5. A J Canta
  1. aNewcastle General Hospital, bRoyal Victoria Infrmary, Newcastle upon Tyne
  1. and reprint requests to: Dr S Hoare, Paediatric Department, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE.

Abstract

A child with colitis was treated for Crohn’s disease, diagnosed on history, clinical and colonoscopic findings, radiolabelled white cell bowel scan, and colonic histology. After septicaemia caused by an unusual organism, further investigation lead to a diagnosis of chronic granulomatous disease (CGD). The granulomatous colitis of CGD is clinically, histologically, and on white cell scanning, indistinguishable from that in Crohn’s disease and should be considered in atypical cases. Infection with unusual ‘pseudomonads’ should prompt the exclusion of this disorder.

  • chronic granulomatous disease
  • colitis
  • Crohn’s disease

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