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Editor,—Levamisole along with prednisolone has been used in the treatment of steroid dependent minimal change nephrotic syndrome (MCNS) for many years. The only important side effect cited in the study of levamisole in the treatment of MCNS by the British Association for Paediatric Nephrology (BAPN) is neutropenia.1
Laux-End et al report a case of vasculitis with circulating autoantibodies in an 11 year old girl with nephrotic syndrome treated with levamisole.2 Raised levels of aspartate aminotransferase (ALT) have been reported in two out of 11 patients given levamisole for recurrent pyoderma. I wish to report a patient with nephrotic syndrome who developed liver toxicity after four weeks’ treatment with levamisole.3 As far as I am aware there are no reports of liver toxicity in children …