Article Text

Download PDFPDF

Growth hormone deficiency and empty sella in DIDMOAD syndrome: an endocrine study.
  1. A T Soliman,
  2. B Bappal,
  3. A Darwish,
  4. A Rajab,
  5. M Asfour
  1. Department of Paediatrics, Royal Hospital, Muscat, Oman.


    Two girls with DIDMOAD syndrome are presented. One also had severe megaloblastic-sideroblastic anaemia and the other several neurological manifestations. Both were short with defective growth hormone secretion. Computed tomography revealed empty sella in both girls; one had widespread atrophic cortical and cerebellar changes. High doses of thiamine improved the anaemia in the first case, increased C peptide secretion in both, but had no effect on the neurological abnormalities.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.