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Liposomal amphotericin B in hepatic candidosis.
  1. M Sharland,
  2. R J Hay,
  3. E G Davies
  1. Department of Child Health, St George's Hospital Medical School, London.


    A 4 year old girl treated with a standard chemotherapy protocol for acute lymphoblastic leukaemia developed hepatic candidosis during the consolidation phase. This relapsed after a prolonged course of amphotericin B and flucytosine. An eight week course of liposomal amphotericin produced a marked clinical improvement which was sustained for one year. A subsequent relapse was associated with transformation to myelodysplastic leukaemia.

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