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Chemoprophylaxis for pulmonary aspergillosis during intensive chemotherapy.
  1. F Cowie,
  2. S T Meller,
  3. P Cushing,
  4. R Pinkerton
  1. Children's Department, Royal Marsden Hospital, Sutton, Surrey.


    Three children who developed pulmonary aspergillosis while being treated for leukaemia or non-Hodgkin's lymphoma. Each child continued with intensive myelosuppressive chemotherapy regimens during the infection and each was successfully treated with antifungal prophylaxis based on itraconazole by mouth. Amphotericin B was also given during periods of severe neutropenia. No reactivation of the fungal infection was seen.

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