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Coagulation screening tests in high risk neonates: a prospective cohort study.
  1. B K Schmidt,
  2. P Vegh,
  3. M Andrew,
  4. M Johnston
  1. Department of Pediatrics and Pathology, McMaster University, Hamilton, Ontario, Canada.


    Forty seven infants in a prospective cohort of 170 high risk neonates without signs of overt bleeding had abnormal coagulation screening tests within 36 hours of birth. Early thrombocytopenia was a better predictor of prolonged prothrombin times and hypofibrinogenemia than very low birth weight, fetal growth retardation, or poor five minute Apgar scores.

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