Article Text

Download PDFPDF
Paradoxical bone mineralisation in the twin to twin transfusion syndrome.
  1. N J Bishop,
  2. F J King,
  3. P Ward,
  4. J M Rennie,
  5. A K Dixon
  1. MRC Dunn Nutrition Unit, Cambridge.


    We report twin preterm infants with the twin to twin transfusion syndrome, exhibiting grossly different bone densities on chest radiographs. Photonabsorptiometry showed the polycythaemic twin was osteopenic and the anaemic twin osteosclerotic; bone mineral contents were 0.028 g/cm and 0.074 g/cm respectively (normal mean (SD) 0.041 (0.006) g/cm. We speculate that alterations in macrophage derived osteoclastic activity contribute to these previously unreported findings.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.