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Increased concentrations of D-dimers in newborn infants.
  1. I R Hudson,
  2. B E Gibson,
  3. J Brownlie,
  4. B M Holland,
  5. T L Turner,
  6. R G Webber
  1. Royal Hospital for Sick Children, Yorkhill, Glasgow.


    The concentrations of D-dimers (the D fragments of fibrinogen) were measured in blood from 15 preterm infants, and 45 born at full term, to establish normal ranges. The adult normal range is less than 0.25 mg/l; 31 of the 60 infants (52%) had values less than 0.25 mg/l, in 16 (27%) they were 0.25-0.5, in eight (13%) 0.5-1, in three (5%) 1-2, and in two (3%) 2-4. D-dimer concentrations measured during the neonatal period should be interpreted with caution.

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