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Myopathy with hypophosphatasia.
  1. S S Seshia,
  2. G Derbyshire,
  3. J C Haworth,
  4. J Hoogstraten
  1. Section of Pediatric Neurosciences, University of Manitoba, Children's Hospital, Winnipeg, Canada.


    Three children with hypophosphatasia also had muscle pains, stiffness, and symptoms of proximal lower limb muscle weakness that occurred early in the disorder and were the presenting features in two. A non-progressive myopathy may be an important sign of hypophosphatasia.

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