Article Text

Download PDFPDF
Newborn splenic volumes vary under different malaria endemic conditions.
  1. J A Corkill,
  2. B J Brabin,
  3. D F MacGregor,
  4. M P Alpers,
  5. R D Milner
  1. Department of Paediatrics, University of Sheffield, Children's Hospital.

    Abstract

    Ultrasound was used to measure newborn splenic dimensions and calculate the volumes in a malarious and a non-malarious region of Papua New Guinea. The median splenic volume of infants born in Madang, where malaria transmission is high throughout the year, was 5.2 cm3/kg, while that of infants born in Goroka, where malaria is not endemic, was 2.6 cm3/kg. The cause of this difference is unknown, but possible explanations include fetal exposure to malaria antigens in utero and the high incidence of inherited red cell disorders in the malarious regions of Papua New Guinea.

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.