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Growth hormone, suspected gonadotrophin deficiency, and ring 18 chromosome.
  1. S S Abusrewil,
  2. A McDermott,
  3. D C Savage
  1. Bristol Children's Hospital.


    A boy with a ring 18 chromosome karyotype was referred because of short stature; he had growth hormone deficiency and possible hypogonadotrophic hypogonadism. Many children with major chromosomal abnormalities are short, but this case emphasises the need to consider growth hormone deficiency in addition.

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