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Relation between height velocity and fasting insulin concentrations.
  1. P C Hindmarsh,
  2. D R Matthews,
  3. L Di Silvio,
  4. A B Kurtz,
  5. C G Brook
  1. Endocrine Unit, Middlesex Hospital London.


    A linear relation between fasting serum insulin concentration and height velocity was found in 47 normal children. This suggests that doubling of growth velocity at puberty is accompanied by a two to threefold rise in insulin. This implies that insulin dosage should be increased by a similar magnitude in pubertal diabetic children during their growth spurt.

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