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Chromosomes of metastatic retinoblastoma.
  1. H A Daly,
  2. E V Davison,
  3. A D Pearson,
  4. M M Reid,
  5. A W Craft


    Chromosomal abnormalities were detected in the bone marrow of a girl with disseminated retinoblastoma. One of these abnormalities, i(6p), is characteristic of primary retinoblastoma and its presence confirmed the diagnosis of bone marrow infiltration with retinoblastoma. This approach could be extended to study other tumours of childhood.

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