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Effect of pancuronium and pethidine on heart rate and blood pressure in ventilated infants.
  1. V M Miall-Allen,
  2. A G Whitelaw
  1. Department of Paediatrics and Neonatal Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London.


    To investigate cardiovascular effects in 32 ventilated neonates, given either pancuronium or pethidine, computer based data were analysed for five minutes preceding and for 20 minutes after administration of the drugs. Heart rate and direct mean arterial pressure remained unchanged but arterial pressure variability decreased with each drug.

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