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Cushing's disease and craniopharyngioma.
  1. F M Ackland,
  2. R Stanhope,
  3. M A Preece
  1. Department of Growth and Development, Institute of Child Health, London.


    A 14-year old girl presented with growth failure and Cushing's disease. Histological examination confirmed a craniopharyngioma but failed to show that the tumour secreted adrenocorticotrophic hormone. We suggest that her Cushing's disease was caused by hypothalamic dysfunction associated with increased corticotrophin-releasing hormone secretion, secondary to the craniopharyngioma.

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