References ranges for serum alpha 1 antitrypsin at various ages have been constructed using specific protein calibration material (SPS-01). Median values and 5th-95th centile ranges for alpha 1 antitrypsin in cord blood are equivalent to those of the adult. The median concentration falls during the first 6 months of age to rise again to adult values by 12 months. Concentrations in early school age are higher than in normal adults.
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