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Fulminating encephalopathy associated with Shigella flexneri infection.
  1. R Sandyk,
  2. M J Brennan


    Three cases of rapidly fatal encephalopathy associated with Shigella flexneri infection are reported. There was a lack of severe intestinal involvement and absence of metabolic derangement. In all 3 patients, areas of necrosis were present throughout the brains; and in one case pontine haemorrhages and demyelination were seen. This report supports the evidence of a particular neurotoxic effect in shigellosis.

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