Plasma concentrations of gastrin, somatostatin, neurotensin, and enteroglucagon were measured by radioimmunoassay in normal 30- and 45-day-old neonates and age-matched infants with confirmed idiopathic hypertrophic pyloric stenosis. Plasma gastrin and somatostatin concentrations were similar in both groups, whereas neurotensin and enteroglucagon were significantly lower in the pyloric stenosis group.
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