Response to long-term treatment with indomethacin
A 6-month-old boy presented with features of pseudohypoaldosteronism. Considerable quantities of supplemental sodium failed to compensate his natriuresis but indomethacin, a prostaglandin inhibitor, greatly reduced his sodium requirement. Treatment was maintained for 9 months when re-evaluation showed him to be dependent on indomethacin for satisfactory control.
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