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A trial comparing cefaclor with co-trimoxazole in the treatment of acute otitis media.
  1. W Feldman,
  2. H Richardson,
  3. B Rennie,
  4. P Dawson


    A prospective random double-blind controlled trial comparing the efficacy of cefaclor with that of co-trimoxazole in the treatment of otitis media was undertaken. Two hundred and twenty-three children aged 12 years or younger were studied. Both drugs were effective, with clinical cure or improvement in more than 90% of the children. The level of compliance was high and side effects few. Both co-trimoxazole and cefaclor can be considered safe and effective drugs for the treatment of acute otitis media.

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