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A reappraisal of routine marrow examination therapy of acute lymphoblasticv leukaemia.
  1. D K Watson,
  2. A E Robinson,
  3. C C Bailey


    Out of 557 routine marrow examinations performed in children receiving maintenance therapy, or having completed therapy, for acute lymphoblastic leukaemia or non-Hodgkin's lymphoma, only 9 marrow relapses were found. Out of 14 marrow examinations performed because of haematological or clinical indications of possible relapse, only 3 failed to confirm relapse. It is suggested that routine marrow examination to detect relapse is not worthwhile and should be stopped.

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