A problem-orientated case record was used for the investigation and management of neonatal jaundice. Investigation of babies requiring phototherapy rarely showed any abnormality but we consider that such routine investigations are worth retaining. There were problems in the interpretation of moderately low plasma concentrations of thyroxine in small, preterm babies. There was biochemical evidence of hepatitis in 3 babies; in all 3 the biochemical abnormality was mild and had disappeared 6 months later in 2 of them. It may be that mild episodes of the neonatal hepatitis syndrome are more common than have been thought and that such infants have a fairly good prognosis.
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