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Control of life-threatening bleeding by combined plasmapheresis and immunosuppressive treatment in a haemophiliac with inhibitors.
  1. T Révész,
  2. J Mátyus,
  3. B Goldschmidt,
  4. V Harsanyi


    Life-threatening lingual haemorrhage was successfully treated in a 3-year-old haemophiliac who had a high level of inhibitor in his plasma. Repeated plasma exchange with high-dose factor VIII concentrate led to a cessation of bleeding. Immunosuppressive treatment introduced at the time of plasmapheresis and carried out for 6 weeks seems to have prevented the return of the inhibitor.

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