You are here

Article Text

Article menu
Download PDFPDF
Research Article
Chloramphenicol and phenobarbitone--a drug interaction.
  1. R A Bloxham,
  2. G M Durbin,
  3. T Johnson,
  4. M H Winterborn

    Abstract

    Two infants with meningitis who were treated with phenobarbitone and high-dose chloramphenicol showed progressive falls in the peak blood levels of chloramphenicol. A standard chloramphenicol dose of 50 mg/kg daily would have produced subtherapeutic blood levels after only a few days. The importance of measuring serial blood chloramphenicol concentrations is stressed.

    https://doi.org/10.1136/adc.54.1.76

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.