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Research Article
Serial studies of numbers of circulating T and B lymphocytes in children with acute lymphoblastic leukaemia.
  1. M M Reid,
  2. A W Craft,
  3. J A Todd

    Abstract

    Serial studies of numbers of circulating T and B lymphocytes at monthly intervals in children with acute lymphoblastic leukaemia showed a marked fall in the number of B cells, relatively greater than that of T cells, early in the course of maintenance chemotherapy and immediately after a course of cranial irradiation. The fall in the number of B cell is not a consequence of long-term chemotherapy, and is possibly related to a specific event such as cranial irradiation.

    https://doi.org/10.1136/adc.52.3.245

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