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Neonatal pyridoxine responsive convulsions due to isoniazid therapy.
  1. S A McKenzie,
  2. A J Macnab,
  3. G Katz


    A 17-day-old infant on isoniazid therapy 13 mg/kg daily from birth because of maternal tuberculosis was admitted after 4 days of clonic fits. No underlying infective or biochemical cause could be found. The fits ceased within 4 hours of administering intramuscular pyridoxine, suggesting an aetiology of pyridoxine deficiency secondary to isoniazid medication.

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