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Research Article
Sexual precocity associated with a hypothalamic tumour. Effects of sex hormone therapy.
  1. R David,
  2. J Rawlinson,
  3. K M Ferguson

    Abstract

    A case of sexual precocity of unusually early onset and associated with a hypothalamic tumour is described. The effects of ethinyl oestradiol and medroxyprogesterone acetate treatment have been monitored by plasma testosterone, FSH, and LH estimations. The results suggested a partial suppression of the tumour's influence, the mechanism of which is discussed.

    https://doi.org/10.1136/adc.50.2.157

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