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Antibodies to Epstein-Barr and other viruses in children with acute lymphoblastic leukaemia
  1. R. N. P. Sutton,
  2. S. D. Marston,
  3. H. J. M. Pullen,
  4. C. W. Darby,
  5. D. I. K. Evans,
  6. R. T. D. Emond


    Sixty-eight children with acute lymphoblastic leukaemia were tested for antibodies to Epstein-Barr (EB) virus and to other viruses. The antibody response to the test viruses in these children was unremarkable, with the exception of EB virus, where the presence of complement-fixing antibodies in children tested during the first month of their illness suggested that a higher proportion had previous experience with this virus than was the case in control children. The implications of this observation with regard to leukaemogenesis are discussed.

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