A study has been made of children born with radial clubbed hands, with reference to the incidence of coexisting congenital heart malformations. In this series of 61 patients with radial clubbed hands 8 had proven heart disease, with a wide variety of congenital cardiac defects.
Thalidomide ingestion was known to have occurred in 9 cases, but may well have been causative in a larger number. But in those cases of radial clubbed hand associated with congenital heart disease, thalidomide appeared not to be causative.
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