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Growth of Children with Thalassaemia
  1. C. Kattamis,
  2. N. Touliatos,
  3. S. Haidas,
  4. N. Matsaniotis

    Effect of Different Transfusion Regimens


    Growth was studied in 74 children with homozygous β-thalassaemia aged 1 to 11 years, treated with three different transfusion regimens.

    In group I (38 cases) haemoglobin levels were maintained above 8 g./100 ml.; in group II (14 cases), pretransfusion haemoglobin levels ranged between 6 and 8 g./100 ml.; in group III (22 children), pretransfusion haemoglobin levels were below 6 g./100 ml.

    Children in group I grew normally, both in weight and height; those in groups II and III were retarded, particularly those in group III.

    Frequent transfusions, in spite of their disadvantages, at present constitute the treatment of choice.

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    Effect of Different Transfusion Regimens