Abstract

Differential clearances of five plasma proteins were studied in 37 north Indian children with the nephrotic syndrome, and these, and the serum β_1c levels were related to steroid response and, in some, renal biopsy histology. 16 children (43%) did not respond completely to steroids and a majority of them had a poorly selective proteinuria. The differential protein clearances suggest that these patients are a heterogeneous group. The serum complement β_1c levels in nephrotics were significantly lower than in control Indian and European children.