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Accuracy of point-of-care testing for the diagnosis of respiratory pathogens in a paediatric intensive care setting
  1. Hannah Norman - Bruce1,
  2. Kathryn Wilson1,2,
  3. Samir Waheed1,
  4. Julie Richardson2,
  5. Helen Groves1
  1. 1 Queen's University Belfast, Belfast, UK
  2. 2 Paediatric Intensive Care Unit, Royal Belfast Hospital for Sick Children, Belfast, Belfast, UK
  1. Correspondence to Dr Hannah Norman - Bruce, Queen's University Belfast, Belfast, UK; hnormanbruce01{at}qub.ac.uk

https://doi.org/10.1136/archdischild-2024-326886

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    Respiratory tract infections contribute significantly to paediatric intensive care unit (PICU) admissions. Early diagnosis supports treatment, cohorting and antimicrobial stewardship. Rapid point-of-care (POC) multiplex PCR techniques show promise in improving antimicrobial and investigation stewardship across healthcare settings.1 However, debate exists regarding their role and accuracy.2 3 We sought to evaluate the feasibility and accuracy of respiratory pathogen POC testing in our PICU.

    All patients admitted to the regional Northern Ireland PICU undergo nasal/nasopharyngeal swab respiratory pathogen POC testing. The BioFire FilmArray BFRP2.1 panel (table 1) is used which provides results in under an hour. Simultaneously, laboratory-based viral and microbiological testing is performed at the clinician’s discretion. All laboratory testing is undertaken by the …

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    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.