• Mortality

The amazing story of the use of azithromycin prophylaxis in low-resource countries continues with the publication of the AVENIR study (Azithromycine pour la Vie des Enfants au Niger: Implementation et Recherche) based in Niger by O’Brien KS et al (N Engl J Med 2024;391(8):699–709 DOI: 10.1056/NEJMoa2312093). Maitland K and Walker SA (N Engl J Med 2024;391:760–762. DOI: 10.1056/NEJMe2407000) describe the history of this work in Africa, and this editorial deserves a read before looking at the main study. The focus of these randomised controlled studies was to prevent trachoma. They describe a study from Ethiopia from …