Rifampin urinary excretion to predict serum targets in children with tuberculosis: a prospective diagnostic accuracy study

Tania A Thomas; Saning'o Lukumay; Sijia Yu; Prakruti Rao; Anna Siemiątkowska; Leonid Kagan; Domitila Augustino; Paulo Mejan; Restituta Mosha; Deborah Handler; Kristen Petros de Guex; Blandina Mmbaga; Herman Pfaeffle; Robert Reiss; Charles A Peloquin; Christopher Vinnard; Estomih Mduma; Yingda L Xie; Scott K Heysell

doi:10.1136/archdischild-2022-325250

Article info

Global child health

Rifampin urinary excretion to predict serum targets in children with tuberculosis: a prospective diagnostic accuracy study

Authors

Tania A Thomas Department of Medicine, Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA PubMed articles Google scholar articles
Saning'o Lukumay Department of Global Health Research, Haydom Lutheran Hospital, Mbulu, Tanzania, United Republic of PubMed articles Google scholar articles
Sijia Yu Pharmacy, Rutgers The State University of New Jersey, New Brunswick, New Jersey, USA PubMed articles Google scholar articles
Prakruti Rao Department of Medicine, Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA PubMed articles Google scholar articles
Anna Siemiątkowska Pharmacy, Rutgers The State University of New Jersey, New Brunswick, New Jersey, USA Pharmacy, Poznań University, Poznan, Poland PubMed articles Google scholar articles
Leonid Kagan Pharmacy, Rutgers The State University of New Jersey, New Brunswick, New Jersey, USA PubMed articles Google scholar articles
Domitila Augustino Department of Global Health Research, Haydom Lutheran Hospital, Mbulu, Tanzania, United Republic of PubMed articles Google scholar articles
Paulo Mejan Department of Global Health Research, Haydom Lutheran Hospital, Mbulu, Tanzania, United Republic of PubMed articles Google scholar articles
Restituta Mosha Department of Global Health Research, Haydom Lutheran Hospital, Mbulu, Tanzania, United Republic of PubMed articles Google scholar articles
Deborah Handler Department of Medicine, Infectious Diseases, Rutgers New Jersey Medical School, Newark, New Jersey, USA PubMed articles Google scholar articles
Kristen Petros de Guex Department of Medicine, Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA PubMed articles Google scholar articles
Blandina Mmbaga Department of Pediatrics, Kilimanjaro Christian Medical College, Moshi, Tanzania, United Republic of PubMed articles Google scholar articles
Herman Pfaeffle Department of Medicine, Naval Medical Center Portsmouth, Portsmouth, Virginia, USA PubMed articles Google scholar articles
Robert Reiss Department of Medicine, Infectious Diseases, Rutgers New Jersey Medical School, Newark, New Jersey, USA PubMed articles Google scholar articles
Charles A Peloquin Pharmacy, University of Florida, Gainesville, Florida, USA PubMed articles Google scholar articles
Christopher Vinnard Department of Medicine, Infectious Diseases, Rutgers New Jersey Medical School, Newark, New Jersey, USA PubMed articles Google scholar articles
Estomih Mduma Department of Global Health Research, Haydom Lutheran Hospital, Mbulu, Tanzania, United Republic of PubMed articles Google scholar articles
Yingda L Xie Department of Medicine, Infectious Diseases, Rutgers New Jersey Medical School, Newark, New Jersey, USA PubMed articles Google scholar articles
Scott K Heysell Department of Medicine, Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA PubMed articles Google scholar articles

Correspondence to Dr Scott K Heysell, University of Virginia, Charlottesville, VA 22908, USA; skh8r{at}uvahealth.org

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Citation

Thomas TA, Lukumay S, Yu S, et al

Rifampin urinary excretion to predict serum targets in children with tuberculosis: a prospective diagnostic accuracy study

Archives of Disease in Childhood 2023;108:616-621.

Publication history

Received December 16, 2022
Accepted April 13, 2023
First published April 25, 2023.

Online issue publication

July 19, 2023

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