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We know that nearly a third of children with peanut allergy will outgrow their response by the age of six and if you introduce peanut protein as early as 4–6 months of age, this will substantially reduce the development of peanut allergy later in childhood. Is there a role for desensitisation and can desensitisation work in children less than 4 years of age? Greenhawt M et al [N Engl J Med 2023; 388:1755–1766 DOI: 10.1056/NEJMoa2212895] enrolled 362 children, aged 1–3 years with peanut allergy in a multicentre, double-blind, randomised, placebo-controlled trial; the phase 3 Epicutaneous Immunotherapy in Toddlers with …
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