Archives of Disease in Childhood: 108 (6)

Highlights from this issue

Atoms (18 May, 2023) Free
Nick Brown

Editorial

Identifying and preventing fraudulent participation in qualitative research (17 April, 2023)
Kerry Woolfall

Clinical law for clinical practice

Clinical law: what do paediatricians want to know? (9 December, 2022)
Robert Wheeler, Francesca Stedman, Nigel J Hall

Review

Liver disease in adolescents (27 September, 2022)
Sunitha Vimalesvaran, Marianne Samyn, Anil Dhawan

This article gives an overview of liver disease in adolescents, covering initial evaluation, clinical management, and the importance of a holistic and developmentally appropriate approach.

Global child health

Digital tools to improve parenting behaviour in low-income settings: a mixed-methods feasibility study (28 March, 2023)
Lena Jäggi, Leonel Aguilar, Milagros Alvarado Llatance, Andreana Castellanos, Guenther Fink, Kristen Hinckley, Maria-Luisa Huaylinos Bustamante, Dana Charles McCoy, Hector Verastegui, Daniel Mäusezahl, Stella Maria Hartinger Pena
Cerebral artery conditional blood velocity in sickle cell disease: a multicentre study and evidence for active treatment (3 February, 2023)
Emmanuel Modebe, Charles Nonyelu, Augustine Duru, Osita Ezenwosu, Barth Chukwu, Anazoeze Madu, Chinedu Ezekekwu, John Aneke, Mildred Izuka, Chisom Nri-Ezedi, Oluomachi Nnachi, Alozie Eze, Ifeoma Ajuba, Emeka Okwummuo, Jane Chilaka, Chinenye Onodugo, Uwaoma Fidelis-Ewa, Obineche Agwu, Ikechukwu Anigbogu, Ebele Muoghalu, Helen Okoye, Chilota Efobi, Obiora Ejiofor, Ngozi Ugwu, Collins Maduka, Nneka Iloanusi, Angela Ugwu, Chide Okocha, Thomas Ulasi, Iheanyi Okpala

Paediatric emergency medicine

Invasive bacterial infection in children with fever and petechial rash in the emergency department: a national prospective observational study (4 April, 2023)
Pilar Storch-De-Gracia, Jose Luis Fernández, Roberto Velasco, Itsaso Saez, Rocío Rodrigo, Sandra Yañez, Ester Castellarnau, Elena Gil, Patricia del Rio, Estíbaliz Garrido, Antón Castaño, Álvaro Perez, María Cabrerizo, María Hernández, Juan Jesús Pérez, María José de la Torre, Gemma Nadal, Javier Martínez, Victoria Sánchez-Tatay

Viewpoint

Immunomodulatory therapy in dengue: need for clinical trials and evidence base (9 June, 2022)
C S Bhat, R Shetty, Balasubramanian Sundaram, A V Ramanan
Ethnicity, child health and paediatric services (27 June, 2022)
Zeshan Qureshi, Alexandra Richards, Camilla C Kingdon, Ian Sinha, Oluwakemi Lokulo-Sodipe, Anna M Rose

Original research

High-flow oxygen therapy in moderate to severe bronchiolitis: a randomised controlled trial (20 March, 2023)
Louise Kooiman, Fenneke Blankespoor, Roy Hofman, Arvid Kamps, Monique Gorissen, Anja Vaessen-Verberne, Ingrid Heuts, Jolita Bekhof
Ten-year survival of children with trisomy 13 or trisomy 18: a multi-registry European cohort study (7 March, 2023)
Svetlana V Glinianaia, Judith Rankin, Joachim Tan, Maria Loane, Ester Garne, Clara Cavero-Carbonell, Hermien E K de Walle, Miriam Gatt, Mika Gissler, Kari Klungsøyr, Natalie Lelong, Amanda Neville, Anna Pierini, David F Tucker, Stine Kjaer Urhoj, Diana Gay Wellesley, Joan K Morris
Population-based screening methods in biliary atresia: a systematic review and meta-analysis (16 February, 2023) Free
Adam Arshad, Julian Gardiner, Carmen Ho, Philippa Rees, Karan Chadda, Alastair Baker, Alastair G Sutcliffe
Low yield from imaging after non-E. coli urine tract infections in children treated in primary care and emergency department
(3 March, 2023)
Yincent Tse, Charlie Pickles, Stephen Owens, Michal Malina, Richard Peace, Milan Gopal
Reference centiles for infant sleep parameters from 4 to 16 weeks of age: findings from an Irish cohort (21 March, 2023)
Marc Paul O Sullivan, Vicki Livingstone, Irina Korotchikova, Eugene M Dempsey, Deirdre M Murray, Geraldine B Boylan
Interventions in primary and community care to reduce urgent paediatric hospital admissions: systematic review (17 February, 2023)
Smita Dick, Clare MacRae, Claire McFaul, Philip Wilson, Stephen W Turner
Factors related to adverse long-term outcomes after mild traumatic brain injury in children: a scoping review (31 March, 2023)
Sharea Ijaz, Lauren Scott, Sarah Dawson, Rebecca Wilson, Joni Jackson, Kate Birnie, Maria Theresa Redaniel, Jelena Savović, Ingram Wright, Mark D Lyttle, Julie Mytton
Robustness of reported postacute health outcomes in children with SARS-CoV-2 infection: a systematic review (2 September, 2022)
Julian Hirt, Perrine Janiaud, Viktoria Luise Gloy, Stefan Schandelmaier, Tiago V Pereira, Despina Contopoulos-Ioannidis, Steven N Goodman, John Ioannidis, Klaus Munkholm, Lars G Hemkens

PostScript

Letter: Breathing by example (21 April, 2023)
Kathryn Kimber, Amanda Equi

Miscellanea

Archivist: More on RSV – vaccine during pregnancy (18 May, 2023)
Archivist: Childhood origins of adult disease (18 May, 2023)
Images in paediatrics: Urethroliths – a rare complication of urethral reconstruction (12 January, 2023)
Jaya Suresh Babu, Henry Puthenveettil Yesodharan
Lucina: Highlights from the literature (18 May, 2023)

Electronic page

Abstracts from the Neonatal and Paediatric Pharmacists Conference 2023

1 Placental pharmacology studies to characterize the effects and disposition of pharmaceuticals: lessons from human tissues and cells for improving drug safety in pregnancy (18 May, 2023) Free
Rick Greupink
2 Pitfalls and opportunities for centralized TDM services: a Belgian singe-centre experience (18 May, 2023) Free
Pieter De Cock
3 The exposure to and efficacy of doravirine in pregnant women as assessed by physiologically-based pharmacokinetic modelling (18 May, 2023) Free
Hedwig van Hove, Vera Bukkems, Damian Roelofsen, Jolien Freriksen, Joris van Drongelen, Elin Svensson, Angela Colbers, Rick Greupink
4 Risks associated with antidepressants in patients with hypertension during pregnancy: a retrospective cohort study (18 May, 2023) Free
Peter Ter Horst, Marlieke Oude Weernink, Elvera Damer, Mireille Edens, Marieke Hemels
5 The perceived barriers and facilitators for model-informed dosing in pregnancy: a qualitative stakeholder analysis (18 May, 2023) Free
Charlotte Koldeweij, Mirèse Kleuskens, Liesbeth Scheepers, Bryony Dean Franklin, Carlijn Litjens, Saskia de Wildt
6 PBPK model-informed dosing guidelines in pediatric clinical care – initiation and drug prioritization (18 May, 2023) Free
Jolien Freriksen, Marika de Hoop-Sommen, Joyce van der Heijden, Rick Greupink, Saskia de Wildt
7 Collaboration in neonatal and paediatric clinical pharmacology: involving medical students within (Inter)national clinical trial networks (18 May, 2023) Free
Sabina Pavlíková, Eva Degraeuwe, Tessa van der Geest, Laura Persijn, Pernilla Skovby, Esther Montero, Anna Negrini, Paul Malenfant, Ricardo Fernandes, Johan van de Walle, Mark Turner, Ondřej Slanař, Pavla Pokorna
8 The influence of sepsis on the tissue penetration of piperacillin-tazobactam in children: a microdialysis study in the juvenile pig (18 May, 2023) Free
Eline Hermans, Freya Meganck, Peter de Paepe, Johan Vande Walle, Pieter de Cock, Mathias Devreese
9 The flood of study feasibilities and the value of a centralised approach (18 May, 2023) Free
Eva Degraeuwe, Laura Persijn, Lieve Nuytinck, Ann Raes, Mark Turner, Johan Vande Walle
10 Paediatric clinical trial needs and requirements within Belgium (18 May, 2023) Free
Eva Degraeuwe, Laura Persijn, Lieve Nuytinck, Ann Raes, Mark Turner, Johan Vande Walle
11 Clinical, methodological and patient/parent expert advice in paediatric drug development via conect4children (18 May, 2023) Free
Fenna Mahler, Katharine Cheng, Irja Lutsar, Begonya Nafria Escalera, Mark Turner, Saskia de Wildt
12 Collaboration in neonatal and paediatric clinical pharmacology: creating a peer-based mentoring platform in a pan-European clinical trial network (18 May, 2023) Free
Eva Degraeuwe, Tessa van der Geest, Laura Persijn, Esther Montero Campos, Mark Turner, Johan Vande Walle
13 Feasibility of the pragmatic PBPK modelling approach – towards model-informed dosing in paediatric clinical care (18 May, 2023) Free
Joyce van der Heijden, Jolien Freriksen, Marika de Hoop-Sommen, Rick Greupink, Saskia de Wildt
14 A comparison of age-banded and weight-based oral paracetamol dosing in hospitalised children (18 May, 2023) Free
Kirstie Wright, Jennie Craske, Andrea Gill, John Jenson, Philip Arnold
15 The relation between the serum trough concentration of paracetamol and pain reduction in preterm and term neonates: a retrospective observational study (18 May, 2023) Free
Roland B van den Berg, AR Céleste Laarman, Jacob A Dijkstra, Agnes I Veldkamp, Eleonora L Swart, Mirjam M van Weissenbruch
16 Poor availability of age-appropriate drug formulations in DR Congo: a barrier to switch from intravenous to oral antibiotics in children admitted to Kisantu hospital (18 May, 2023) Free
Bieke Tack, Daniel Emmanuel, Japhet Vita, Ntangu Ngina, Octavie Lunguya, Dina Vangeluwe, Karel Allegaert, Rafaella Ravinetto
17 Microdosing/microtracer based pediatric drug development (18 May, 2023) Free
Esther van Duijn, Steven Erpelinck, Wouter Vaes
18 In vitro investigation of vancomycin-induced kidney injury: development of a 2D cellular model (18 May, 2023) Free
Lawrence Rhodes, Stephen McWilliam, Amy Chadwick
19 The inflammation in the pathology of patients with mucopolysaccharidosis (18 May, 2023) Free
Anna-Maria Wiesinger, Florian Lagler, Brian Bigger, Christoph Kampmann, Roberto Giugliani, Maurizio Scarpa
20 Predicting treatment response to vancomycin using bacterial DNA load as a pharmacodynamic marker in premature and very low birth weight neonates: a population PKPD study (18 May, 2023) Free
Amadou Samb, Koos Dijkstra, Frank van de Dungen, Timo de Haan, Ron Mathôt, Mirjam van Weissenbruch
21 Physiologically based pharmacokinetic model to simulate midazolam pharmacokinetics in a paediatric US population (18 May, 2023) Free
Trevor Johnson, Fiskani Kondowe, Iain Gardner
22 Favipiravir pharmacokinetics in immunocompromised infants and children with chronic RNA viral infections (18 May, 2023) Free
Iek Cheng, Caroline Solas, Evey Howley, Judith Breuer, Joseph Standing, Alexandra Kreins
23 Plasma renin activity in young children with heart failure: influence of age, disease and ACE inhibitor treatment (18 May, 2023) Free
Melina Steichert, Willi Cawello, Johannes MPJ Breur, Christoph Male, Saskia N de Wildt, Stephanie Läer
24 Antipsychotics use and weight gain in children compared to adults: analysis of spontaneous adverse drug reaction reports (18 May, 2023) Free
Florentia Kaguelidou, Zaba Lieber, Francois Montastruc, Genevieve Durrieu, Jean-Marc Treluyer, Laurent Chouchana
25 Point prevalence study of paediatric polypharmacy (18 May, 2023) Free
James Moss, Asia Rashed, John Jensen, John Wilson, Lauren Walker, Daniel Hawcutt
26 Introduction of the project of the czech drug database in neonatology and pediatrics in 2022 (18 May, 2023) Free
Sabina Pavlíková, Petra Rozsívalová, Petr Kulíšek, Pavla Pokorná
27 Risk factors of augmented renal clearance in critically ill children using iohexol clearance for renal function assessment (18 May, 2023) Free
Evelyn Dhont, Tatjana Van Der Heggen, Evelien Snauwaert, Jef Willems, Johan Vande Walle, Pieter de Cock
28 Paediatric medication error prevention (PMEP) a tripartite alliance working together (18 May, 2023) Free
Pramodh Vallabhaneni, Aamina Ahmad, Rachel Issac, Nicola Fitchett, Bhavee Patel
29 What domains related to medicines were measured in studies of burden of care for paediatric patients? A systematic review (18 May, 2023) Free
Tharshiya Thatparan, Julien Marro, Daniel Hawcutt
30 Utilization of and barriers to individual treatment trials in mucopolysaccharidosis – interim results of an expert survey (18 May, 2023) Free
Anna-Maria Wiesinger, Florian Lagler, Maurizio Scarpa, Roberto Giugliani, Christina Lampe, Christoph Kampmann
31 The impact of paediatric dose range checking software (18 May, 2023) Free
Elena Rybka, Matthew Neame, James Moss, Jordi Saez Dominguez, Andrea Gill, Nik Barnes, Daniel Hawcutt
32 Rapid drop in midazolam concentration may be linked to paediatric delirium in critically ill children – an observational pilot study (18 May, 2023) Free
Sabrina Marongiu, Mathieu Bolhuis, Daan Touw, Martin Kneyber
33 Off-label use of drugs in paediatric (specialised) outpatient clinics – what has changed between 2009 and 2019? (18 May, 2023) Free
Irmgard Toni, Jutta Hupfer, Antje Neubert
34 Attitudes of children and young people and their parents towards polypharmacy – pilot study (18 May, 2023) Free
James Moss, Asia Rashed, Lauren Walker, Daniel Hawcutt
35 What is known about the pharmacology of intramuscular therapeutics in duchenne muscular dystrophy? A systematic review (18 May, 2023) Free
Eve Roberts, Jia Yi Gan, Daniel Hawcutt, Stefan Spinty
36 Mapping variation between national and local clinical practice guidelines for acute paediatric asthma from the United Kingdom and the Netherlands (18 May, 2023) Free
Charlotte Koldeweij, Jonathan Clarke, Carmen Rodriguez Gonzalvez, Joppe Nijman, Ian Maconochie, Nicholas Appelbaum
37 Deprescribing long acting beta2 agonists in children and adolescents with stable asthma: a systematic review (18 May, 2023) Free
Wiktoria Drozdz, Ian Sinha, Daniel Hawcutt
38 Innovative high-fidelity simulation for vaccination training of pharmacist including emergency cases - a randomised controlled study (18 May, 2023) Free
Shahzad Sayyed, Ahmed Reda Sharkas, Bushra Ali Sherazi, Armin Dabidian, Holger Schwender, Stephanie Läer
39 KiDSafe – improving medication safety for children and adolescents: implementation and evaluation of a new form of care (18 May, 2023) Free
Irmgard Toni, Dorothée Malonga Makosi, Jochem König, Michael S Urschitz, Wolfgang Rascher, Antje Neubert
Author index (18 May, 2023) Free

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Current Issue

June 2023 - Volume 108 - 6

Highlights from this issue

Editorial

Clinical law for clinical practice

Review

Global child health

Paediatric emergency medicine

Viewpoint

Original research

PostScript

Miscellanea

Electronic page

Abstracts from the Neonatal and Paediatric Pharmacists Conference 2023

Issue Information

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Current Issue

June 2023 - Volume 108 - 6

Highlights from this issue

Editorial

Clinical law for clinical practice

Review

Global child health

Paediatric emergency medicine

Viewpoint

Original research

PostScript

Miscellanea

Electronic page

Abstracts from the Neonatal and Paediatric Pharmacists Conference 2023

Issue Information