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High-flow oxygen therapy in moderate to severe bronchiolitis: a randomised controlled trial
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  • Published on: 19 April 2024
    High-flow oxygen therapy in moderate to severe bronchiolitis: a randomised controlled trial.

    Most of the results in table 3 express the difference as high flow minus low flow except for two in the section "VWS (hours) at 6 and 12 hours "that use low flow minus high flow.
    In the abstract the primary outcome is expressed as low flow minus high flow while in Table 3 it is expressed as high flow minus low flow.
    This is an underpowered study and rather than say "we find no measurably clinically relevant benefit in the use of HF compared with LF in hypoxic children......" would it be more accurate to say "we conclude there is insufficient evidence to show a difference in HF versus LF....", ie. this is called a Type 2 error.

    Conflict of Interest:
    None declared.