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Images in paediatrics
Nasopharyngeal glial heterotopia, ectopic pituitary and craniopharyngeal canal
  1. Aikaterini Perogiannaki1,
  2. Julie Chandra2,
  3. Charles Buchanan3,
  4. Ved Bhushan Arya3,4,
  5. Nicholas WM Thomas5,
  6. Bassel Zebian5,
  7. Ritika R Kapoor3,4
  1. 1 Department of Paediatric Endocrinology, University College Hospital, London, UK
  2. 2 Department of Neuroradiology, King's College Hospital, London, London, UK
  3. 3 Department of Paediatric Endocrinology, King's College Hospital, London, UK
  4. 4 Faculty of Medicine and Life Sciences, King's College London, London, UK
  5. 5 Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, UK
  1. Correspondence to Dr Aikaterini Perogiannaki, Paediatric Endocrinology, University College Hospital, London, London, UK; a.perogiannaki{at}

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A 2-month-old boy presented with marked nasal obstruction, cyanotic episodes and severe respiratory distress without relevant antenatal/family history. He had multiple investigations including a CT scan to exclude facial bony abnormalities. CT scan showed a postnasal space mass, arising from the base of the skull. MRI confirmed a midline nasopharyngeal soft tissue lesion in continuity with the pituitary gland via a large patent craniopharyngeal canal (CPC) (figure 1), a sphenoid bone congenital defect connecting the sella and nasopharynx.1 The nasopharyngeal mass was continuous with a dysplastic and inferiorly displaced anterior pituitary gland. …

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  • Contributors AP reviewed the notes, gained consent and wrote the article, JC reviewed the imaging and wrote the legends. AP and JC contributed equally to this paper. RK conceptualised the article and supervised the project.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.