July 2022 - Volume 107 - 7
Global child health
- Children living with disabilities are neglected in severe malnutrition protocols: a guideline review (4 February, 2022)
This paper outlines the case for more inclusion of children living with disability in clinical guidelines for severe malnutrition, as malnutrition is common in children with neurodevelopmental disability and requires some different approaches.
- World Health Organization and knowledge translation in maternal, newborn, child and adolescent health and nutrition (30 December, 2021)
Members of the World Health Organization's Strategic and Technical Advisory Group of Experts shares some insights on their approach to knowledge translation to improve child health worldwide.
Paediatric emergency medicine
- Extra-axial haemorrhages in young children with skull fractures: abuse or accident? (21 February, 2022)
An observational cohort study comparing extra-axial haemorrhages in children with a known accidental cause and known abusive causes.
Clinical law for clinical practice
- Time to normalisation of tissue transglutaminase in paediatric coeliac disease is dependent on initial titre and half of patients will normalise within 12 months (28 February, 2022)
This study explores the relationship of tissue transglutaminase antibody titres to symptoms and the time to normalisation in a cohort of patients with coeliac disease.
- Data handling practices and commercial features of apps related to children: a scoping review of content analyses (10 February, 2022)
A scoping review of apps related to children finds that data privacy and commercial features are rarely evaluated. These apps show frequent data sharing, manipulative delivery of In-app purchases and advertisements with content that is potentially harmful to child health.
- Long COVID (post-COVID-19 condition) in children: a modified Delphi process (1 April, 2022)
How might one understand long covid in children? One way is to arrive at a consensus on a research definition. The authors describe a modified Delphi approach, which included people with lived experience, research and service delivery.
- Information for children and young people about reporting suspected adverse drug reactions (15 March, 2022)
In a QI project, Hawcutt et al report the development of a guide to help CYP report adverse events to medication via the MHRA's yellow card system.
- Assessment of mitochondrial toxicity in newborns and infants with congenital cytomegalovirus infection treated with valganciclovir (14 March, 2022)
Some antivirals are associated with mitochondrial toxicity due to off-target inhibition of DNA-polymerases. This study looks for evidence of mitochondrial toxicity in infants with congenital CMV infection, treated with valganciclovir. In a series of experiments no evidence of mitochondrial toxicity was found.